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THE DAYS OF NOAH… And Why We Should Hit Pause On Human Gene Editing

In a recent article in Discover Magazine entitled “We Must Never Allow Our Technology to Eclipse Our Humanity,” Collins called for a “moratorium of at least five years on heritable human gene editing.” Heritable gene editing technologies, like “Prime Editing,” aim to edit genes that can be passed on to future generations, along with any unintended and dangerous mutations. This differs from “non-heritable gene editing,” which can be used to treat people with “life-threatening disorders, such as sickle cell disease, HIV infection, cancer and muscular dystrophy.” Proponents of Prime Editing talk about the possibility of making “any kind of DNA change that anyone wants at just about any site in the human genome.” Thus, according to Collins, “scientists and leaders around the globe have an obligation to consider the appropriate use — if any — of heritable human gene editing. This involves scrutinizing the safety of such experiments, including the risk of unintended mutations, as well as a clear-eyed analysis of actual medical need… (READ MORE)


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